In 2006, three months before their wedding ceremony, Mai is diagnosed with a difficult case of anti NMDA receptor encephalitis, a rare disease which only affects one in three million people. As Mai ends up in a coma, Hisashi prays for her recovery. Miraculously, she regains consciousness only to gradually lose memory of her husband due to a memory disorder. Nevertheless, Hisashi keeps going back to his wife, enduring the pain associated with it, and after eight long years, a miracle happens.
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