Shinonome Mei was living her life happily with her two parents, working at the family business. That until some accident happened and both of her parents died. Mei, sad but full of determination, decided to continue with their business. But then, a weird man came, telling her she must take over the Hongou family that is known by being rich and powerful. That way, she finds herself dragged into a big mess, trying to become a lady in a rich school while finding the unpleasant sides of her fate.
They are both about a butler, the young mistress he serves and their surroundings of other butlers and young mistresses. The main heroin is studying at a prestigious academy, while her butler is there to assist her.
In Hayate the Combat Butler they are also young masters, while in Mei-chan no Shitsuji the master can only be a girl.